The MPR workspace is fixed to a 2x2 image box layout. The top left image box always contains the source images from which the MPR was started. Each of the three other image boxes are controlled by its own MPR line (or slice line) drawn on a separate reference image, which are colour-coded and labelled for ease of identification.
The MPR line represents the orientation of the images it controls in much the same way reference lines indicate the positions of images in different display sets relative to each other (you can actually turn on reference lines and see how they coincide with the MPR lines). Every generated image will always extend from the top to the bottom of the stack of reference images. One end of each MPR line is marked with an arrowhead to indicate the orientation of the images it generates – the arrow always points from the left side to the right side of the generated images.
ClearCanvas Vetstation - User's Guide
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